Longevica is a science driven company in search of mechanisms of health extension. Started by a team of scientists and philanthropists, Longevica is guided by indisputable scientific data derived from fundamental experiments and comprehensive models.
Long-lived female mice in the study made it the largest one
Well-characterized pharmacological compounds in one study
Pharmacological classes have been tested
of study including nearly four years of mice experiment
Invested into the study
the second result after rapamycin
A vision to slow down aging and postponing and eliminating age-related diseases
has been established
To identify the mechanisms of life extension an ambitious experiment involving most
well-characterized pharmacological compounds in mice was undertaken
Start of a valid study on the largest
array of pharmacological compounds to find
3.5-year experiment was completed. As a result, 5 compounds showed statistically significant life-extension effect (16-22%).
It became the second result in the history after rapamycin.
With big data analysis we identified two particular classes of compounds of 62 in total that showed statistically significant correlation with life-extension. It gave us a clue on existence of mechanisms of life-extension we had to find.
The team spent next 6 years specifically looking into these compounds, studying its mechanisms of action and history of application in human medicine.
The team managed to formulate valid hypothesis regarding 2 mechanisms of life extension details of which are currently being specified. Both mechanisms aim at fighting toxins accumulation that results in health improvement and life extension. The core of our paradigm of life extension is: fewer toxins -> fewer aged-related diseases -> longer lifespan.
The unique data base in mice combined with human data have been accumulated on a dedicated platform being a source for new therapies and food categories developement.
More to come